Defrin "could not disclose" whether Khamenei is one of Israel's strike targets when asked by a reporter.

Some 204 people have already been wounded by Iranian attacks, along with three killed.

Fire and rescue teams are on the scene searching for people trapped under rubble from impacted buildings, authorities noted.

The jets struck the site, containing Surface-to-Surface Missiles and Cruise Missiles, after receiving guidance from the Intelligence Directorate. 

 “The Israeli economy has been operating for nearly two years in a state of war and has gained significant experience in handling emergency situations."

Israel has taken a substantial bite out of Tehran's nuclear program, but it is far from down for the count.

Trump, for his part, described events in the Middle East as "very alarming," according to Ushakov, the Kremlin's aid.

"We will soon know if it succeeded," an Israeli source told the Jerusalem Post.